Larnell、Luanne带着他们的疯狂搞笑再次回归，由于吸烟引起的怪异副作用，他们前往南美寻求治疗。在深山丛林里，他们遇到了致命的危险……
Based on the novel by Karel Capek, the prominent Czech writer of the early 20th century who coined the word robot for his play R.U.R., the story revolves around a discovery of Krakatit - a powerful explosive - by Prokop, an experimental scientist who, following an accidental explosion in his lab, slips in and out of delirium. When he realises that, in a delirious period, he has given the formula for making Krakatit to one of his colleagues, he tries to find the man, who does not realize how dangerous a thing Krakatit is. In the process, he nearly gives his discovery away again to foreign interests, a group of anarchists, and even greater forces of darkness...
改编自押见修造的同名漫画原著《恶之华》。导演是曾执导《接招吧！那边的女孩》等漫改作品的井口升，编剧则是曾编写《我们仍未知道那天所看见的花的名字》等许多人气动画剧本的冈田磨里。 迷恋法国著名诗人波德莱尔的代表作《恶之花》的中学生主人公春日高男，被同班同学仲村佐和目睹了偷班花佐伯奈奈子体操服的场景，于是被她的各种离谱要求捉弄的故事。
