Many criminals made the mistake of underestimating Lieutenant Columbo, a homicide investigator with a crumpled trench-coat and a beat-up car, who certainly acted as an incompetent bumbler. But he was so polite to every suspect, and he talked so much about his wife (who we never got to see on any episode, but who many believe later had her own show, starring Kate Mulgrew, later of Star Trek: Voyager fame) that he lulled even the shrewdest murderer into a false sense of security. And although the audience had witnessed the murder in the beginning of each episode, it was still a surprise to see what mistakes the killers had made during the seemingly perfect murder.
重案组高级督察韦景声和香港廉政公署高级调查主任贺伟廉在缉凶过程中不期而遇，几经被赃款陷害、杀手追杀，搭档反目后，携手使一个几乎包含了整个香港顶层社会网络的贪腐势力逐渐浮出水面，据悉，该剧有九大案件贯穿始终，且部分案件是由真实事件改编 。
讲述19岁高三时怀孕而不得不放弃学业的女主人公在39岁时与儿子考上同一所大学后发生的故事，崔智友在剧中将饰演为了在丈夫和儿子前扬眉吐气而在将近40岁时再次挑战大学的女主人公。
